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Anna (Luciana Littizzetto) and Piero (Emilio Solfrizzi) struggling with the dull routine of a twenty-year marriage. But one day, a providential accident negates Piero memory, and Anna took the opportunity to “riformattarlo”, trying to turn it in the perfect man… Rocco and Michele (Ficarra and Picone) playing in a Beatles cover band. Rocco is opposed by the companion (Francesca Inaudi), teacher in the same school, and Michele, thanks to the clever lie, manages to keep his wife in the dark (Serena Autieri), a woman manager who believes that the music has stopped. When Rocco, after yet another quarrel in the family, is hosted by Michele, the lie is likely to be unveiled… Marcello (Claudio Bisio) and Paola (Nancy Brilli) are a divorced couple years. The two pretend to be a happy family when they visit the mother of his (Wilma De Angelis) eighty years old and suffering from heart. When a diagnostic cardiologist a few days of life to her grandmother, it asks them to spend with his family at home. The two divorced people find themselves forced to live together and play the part 24 Hour 24!